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ilumina goldengate methylation cancer panel i array  (GoldenGate Software Inc)

 
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    GoldenGate Software Inc ilumina goldengate methylation cancer panel i array
    Ilumina Goldengate Methylation Cancer Panel I Array, supplied by GoldenGate Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/goldengate+methylation+panel/pmc02850313-269-2-2?v=GoldenGate+Software+Inc
    Average 90 stars, based on 1 article reviews
    ilumina goldengate methylation cancer panel i array - by Bioz Stars, 2026-08
    90/100 stars

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    DNA methylation summary characteristics of lymphoma and of healthy B and GCB cells. ( a ) The frequency distribution of the promoter methylation beta values of B-cells shows two maxima referring to almost not- and completely methylated promoters, respectively; The distributions of beta values loose this bimodality to a large degree in lymphoma where weakly and intermediately methylated genes become hyper-methylated and highly methylated genes become hypo-methylated compared with healthy B-cells ( b + c ); ( d ) The total methylation level increases and ( e ) the variability of methylation among the genes in each of the samples decreases.

    Journal: Genes

    Article Title: Epigenetic Heterogeneity of B-Cell Lymphoma: DNA Methylation, Gene Expression and Chromatin States

    doi: 10.3390/genes6030812

    Figure Lengend Snippet: DNA methylation summary characteristics of lymphoma and of healthy B and GCB cells. ( a ) The frequency distribution of the promoter methylation beta values of B-cells shows two maxima referring to almost not- and completely methylated promoters, respectively; The distributions of beta values loose this bimodality to a large degree in lymphoma where weakly and intermediately methylated genes become hyper-methylated and highly methylated genes become hypo-methylated compared with healthy B-cells ( b + c ); ( d ) The total methylation level increases and ( e ) the variability of methylation among the genes in each of the samples decreases.

    Article Snippet: Microarray-derived DNA methylation data (GoldenGate Methylation Cancer Panel I; Illumina, San Diego, CA) of in total 133 samples obtained from hematological neoplasms and reference systems were taken from [ ] in terms of beta values of 1410 CpG’s located in the range of −1500 bp to +500 bp around the transcription start site of 768 genes thus serving as markers for their promoter methylation.

    Techniques: DNA Methylation Assay, Methylation

    SOM portraying of the DNA methylation landscape of lymphoma (MetSOM). ( a ) SOM portraits of histological lymphoma classes and of controls. Red and blue colors assign regions containing genes with high and low methylation levels, respectively; ( b ) the methylation overview map summarizes regions hypermethylated in any of the classes compared with any other one in red. The methylation variance map identifies regions of highly variable (red) and almost invariant (blue) beta values; ( c ) The methylation profiles show the mean methylation level among the samples of genes taken from the “spot” regions 1–6 assigned in the methylation overview map. Horizontal dashed lines serve as guide for the eye showing the mean methylation level of the respective spot averaged over all samples. Assignments as “hyper-” or “hypomethylated” refer to relative methylations compared with B-cells. Lists of genes in these regions are given in .

    Journal: Genes

    Article Title: Epigenetic Heterogeneity of B-Cell Lymphoma: DNA Methylation, Gene Expression and Chromatin States

    doi: 10.3390/genes6030812

    Figure Lengend Snippet: SOM portraying of the DNA methylation landscape of lymphoma (MetSOM). ( a ) SOM portraits of histological lymphoma classes and of controls. Red and blue colors assign regions containing genes with high and low methylation levels, respectively; ( b ) the methylation overview map summarizes regions hypermethylated in any of the classes compared with any other one in red. The methylation variance map identifies regions of highly variable (red) and almost invariant (blue) beta values; ( c ) The methylation profiles show the mean methylation level among the samples of genes taken from the “spot” regions 1–6 assigned in the methylation overview map. Horizontal dashed lines serve as guide for the eye showing the mean methylation level of the respective spot averaged over all samples. Assignments as “hyper-” or “hypomethylated” refer to relative methylations compared with B-cells. Lists of genes in these regions are given in .

    Article Snippet: Microarray-derived DNA methylation data (GoldenGate Methylation Cancer Panel I; Illumina, San Diego, CA) of in total 133 samples obtained from hematological neoplasms and reference systems were taken from [ ] in terms of beta values of 1410 CpG’s located in the range of −1500 bp to +500 bp around the transcription start site of 768 genes thus serving as markers for their promoter methylation.

    Techniques: DNA Methylation Assay, Methylation